產(chǎn)品詳情
簡單介紹：
Anti-phospho-ATF2 (Thr51)抗體產(chǎn)品質(zhì)量穩(wěn)定，實(shí)驗(yàn)效果明顯，貨期快，價格優(yōu)惠，歡迎垂詢訂購！我公司長期供應(yīng)**組化抗體、WB抗體、**組化試劑盒和抗體試驗(yàn)所需全部相關(guān)試劑、熒光標(biāo)記抗體、單克隆抗體、多克隆抗體、各種標(biāo)記的二抗IgG/IgM/IgD/IgA等科研實(shí)驗(yàn)抗體。Anti-phospho-ATF2 (Thr51)抗體用于**組化實(shí)驗(yàn),WB實(shí)驗(yàn),相應(yīng)的標(biāo)記抗體有HRP標(biāo)記抗體,FITC標(biāo)記,BIO等。
詳情介紹：
Rabbit Anti-phospho-ATF2 (Thr51)
Cat. Number:
Anti-phospho-ATF2 (Thr51)抗體XY-5172R
Quantity size:
0.1ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
ATF2 is a member of the Anti-phospho-ATF2 (Thr51)抗體ATF/CREB family of basic region leucine zipper DNA binding proteins that regulates transcription by binding to a consensus cAMP response element (CRE) in the promoter of various viral and cellular genes. Many of these genes are important in cell growth and differentiation, and in stress and immune responses. ATF2 is a nuclear protein that binds DNA as a dimer and can form dimers with members of the ATF/CREB and Jun/Fos families. It is a stronger activator as a heterodimer with cJun than as a homodimer. Several isoforms of ATF2 arise by differential splicing. The stable native full length ATF2 is transcriptionally inactive as a result of an inhibitory direct intramolecular interaction of its carboxy terminal DNA binding domain with the amino terminal transactivation domain. Following dimerization ATF2 becomes a short lived protein that undergoes ubiquitination and proteolysis, seemingly in a protein phosphatase-dependent Anti-phospho-ATF2 (Thr51)抗體mechanism. Stimulation of the transcriptional activity of ATF2 occurs following cellular stress induced by several genotoxic agents, inflammatory cytokines, and UV irradiation. This activation requires phosphorylation of two threonine residues in ATF2 by both JNK/SAP kinase and p38 MAP kinase. ATF2 is abundantly expressed in brain.
Also known as:
ATF2(Phospho-Thr51); Anti-phospho-ATF2 (Thr51)抗體ATF2 (phospho Thr51); ATF2 (phospho T51); p-ATF2 (Thr51); p-ATF2 (T51); CREB 2; HB 16;Activating Transcription Factor 2; ATF 2; Atf-2; ATF2 protein; cAMP Response Element Binding Protein 2; cAMP response element binding protein CRE BP1; cAMP-dependent transcription factor ATF-2; cAMP-responsive element-binding protein 2; CRE BP1; CRE-BP; CREB 2; CREB2; CREBP1; Cyclic AMP dependent transcription factor ATF 2; Cyclic AMP-responsive; ATF2_HUMAN.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, .
●
Immunogen: KLH conjugated Synthesised phosphopeptide derived from human ATF2 around the phosphorylation site of Thr51.
●
Predicted Molecular Weight: 55kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be Anti-phospho-ATF2 (Thr51)抗體determined by the end user.
Not yet tested in other applications.
Optimal working dilutions must be Anti-phospho-ATF2 (Thr51)抗體determined by the end user.
xy-0961M Leptin receptor瘦素受體抗體
xy-11057R Elastin項(xiàng)韌帶彈性蛋白抗體
xy-8574R ox-LDL氧化低密度脂蛋白抗體
xy-5779R LTBP4轉(zhuǎn)化生長因子β結(jié)合蛋白4抗體
xy-5765R LANCL2G蛋白偶聯(lián)受體69B
xy-4581R Listeria tropina李斯特菌菌體蛋白抗體
xy-4213R LARGRho的鳥嘌呤核苷酸交換因子12抗體
xy-6395R LEU5白血病相關(guān)蛋白5抗體
xy-7809R LRRC62富含亮氨酸重復(fù)蛋白62抗體
xy-6963R LPAP**細(xì)胞磷蛋白磷酸酶相關(guān)蛋白抗體
xy-8303R LGI4含亮氨酸神經(jīng)膠質(zhì)瘤失活蛋白4抗體
xy-8305R LYL1**細(xì)胞性白血病相關(guān)序列1抗體
xy-10255R L-CitrullineL-瓜氨酸抗體
xy-3907R Legumain半胱氨酸蛋白酶抗體
xy-6272R LDHD乳酸脫氫酶D抗體
xy-3949R LYK5蛋白激酶LYK5抗體
xy-10220R lipotropin gamma促脂素gamma抗體
xy-5081R Lamin B Receptor核纖層蛋白B受體抗體
xy-5076R Ceramide synthase 1長壽相關(guān)基因lASS1抗體
xy-5080R LASS6長壽相關(guān)基因lASS6抗體
xy-5082R LASS5長壽相關(guān)基因lASS5抗體
xy-5078R LASS3長壽相關(guān)基因lASS3抗體
xy-5077R Ceramide synthase 2腫瘤轉(zhuǎn)移抑制基因1抗體
xy-5079R LASS4長壽相關(guān)基因lASS4抗體
xy-6446R Lin-28BRNA結(jié)合蛋白LIN28B抗體
