產(chǎn)品詳情
簡(jiǎn)單介紹：
Anti-ADAM13抗體產(chǎn)品質(zhì)量穩(wěn)定，實(shí)驗(yàn)效果明顯，貨期快，價(jià)格優(yōu)惠，歡迎垂詢訂購(gòu)！我公司長(zhǎng)期供應(yīng)**組化抗體、WB抗體、**組化試劑盒和抗體試驗(yàn)所需全部相關(guān)試劑、熒光標(biāo)記抗體、單克隆抗體、多克隆抗體、各種標(biāo)記的二抗IgG/IgM/IgD/IgA等科研實(shí)驗(yàn)抗體。Anti-ADAM13抗體用于**組化實(shí)驗(yàn),WB實(shí)驗(yàn),相應(yīng)的標(biāo)記抗體有HRP標(biāo)記抗體,FITC標(biāo)記,BIO等。
詳情介紹：
Rabbit Anti-ADAM13
Cat. Number:
Anti-ADAM13抗體KL-13736R
Quantity size:
0.2ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
ADAM13 was first described as a protein expressed in somatic mesoderm and neural crest cells, in developing Xenopus embryos. ADAM13 was also found in liver, heart, and intestines from ***** Xenopus. ADAM13 may regulate cellular signaling via Src and Src tyrosine kinase. ADAM13 may also act as a cell attachment molecule, by binding integrins through the cysteine rich domain amoung many other roles. A Anti-ADAM13抗體member of the metalloproteinase family containing disintegrin like domains (ADAMs) the functions of ADAM13 are still poorly understood. ADAM13 contains the canonical HExxHxxxxxH zinc metalloproteinase motif, as well as disintegrin, cysteine rich, EFG like, transmembrane and Cytoplasmic domains. ADAM13 has been shown to be proteolytically active, cleaving fibronectin after binding it to the EGF like domain. ADAM13 is also shed from cells in culture, cleaved aminoterminal from the transmembrane domain, and is released into the culture media. Shed ADAM13 is a 52 kD protein, and can form complexes with a2 macroglobulin, suggesting it is a competent protease. Xenopus ADAM13 has greatest homology with human ADAM 33 (51% identical), and is 46% identical with human or mouse ADAM12 or ADAM19. It is still unclear if any of these ADAMs Anti-ADAM13抗體are species orthologs of Xenopus ADAM13, but there are significant differences between the related sequences, suggesting that ADAM13 may be a unique protein. The full length Xenopus ADAM13 sequence codes for a 914 amino acid protein. Predicted mass is 99.749 kD, but glycosylation and cyteine rich regions give Xenopus ADAM13 an apparent MW of 120 kD unprocessed, and 97 kD processed forms, on reduced SDS PAGE gels. ADAM13 contains a putative furin cleavage site, suggesting that a prohormone convertase cleaves the propeptide domain away from the catalytic domain
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Xenopus (Silurana) tropicalis .
●
Immunogen: KLH conjugated synthetic peptide derived from Xenopus (Silurana) tropicalis ADAM13.
●
Predicted Anti-ADAM13抗體Molecular Weight: 68kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications.
Anti-ADAM13抗體Optimal working dilutions must be determined by the end user.
Not yet tested in other applications.
Anti-ADAM13抗體Optimal working dilutions must be determined by the end user.
kl292Hu02 α-胞襯蛋白(SPTAN1)多克隆抗體 Polyclonal Antibody to Alpha-Fodrin (SPTAN1)
kl262Hu02 轉(zhuǎn)鐵蛋白受體2(TFR2)多克隆抗體 Polyclonal Antibody to Transferrin Receptor 2 (TFR2)
kl243Mu02 對(duì)氧磷酶1(PON1)多克隆抗體 Polyclonal Antibody to klaoxonase 1 (PON1)
kl235Mu03 補(bǔ)體1抑制因子(C1INH)多克隆抗體 Polyclonal Antibody to Complement 1 Inhibitor (C1INH)
kl235Mu02 補(bǔ)體1抑制因子(C1INH)多克隆抗體 Polyclonal Antibody to Complement 1 Inhibitor (C1INH)
kl221Mu04 轉(zhuǎn)錄因子20(TCF20)多克隆抗體 Polyclonal Antibody to Transcription factor 20 (TCF20)
kl221Mu03 轉(zhuǎn)錄因子20(TCF20)多克隆抗體 Polyclonal Antibody to Transcription factor 20 (TCF20)
kl220Ra02 腎上腺髓質(zhì)素(ADM)多克隆抗體 Polyclonal Antibody to Adrenomedullin (ADM)
kl207Hu02 谷丙轉(zhuǎn)氨酶(ALT)多克隆抗體 Polyclonal Antibody to Alanine Aminotransferase (ALT)
kl172Mu02 血小板因子4(PF4)多克隆抗體 Polyclonal Antibody to Platelet Factor 4 (PF4)
kl150Hu02 癌胚抗原(CEA)多克隆抗體 Polyclonal Antibody to Carcinoembryonic Antigen (CEA)
kl099Mu02 基質(zhì)金屬蛋白酶13(MMP13)多克隆抗體 Polyclonal Antibody to Matrix Metalloproteinase 13 (MMP13)
kl099Hu02 基質(zhì)金屬蛋白酶13(MMP13)多克隆抗體 Polyclonal Antibody to Matrix Metalloproteinase 13 (MMP13)
kl069Mu02 N-乙酰β-D-氨基葡萄糖苷酶(NAGase)多克隆抗體 Polyclonal Antibody to N-Acetyl Beta-D-Glucosaminidase (NAGase)
kl069Hu02 N-乙酰β-D-氨基葡萄糖苷酶(NAGase)多克隆抗體 Polyclonal Antibody to N-Acetyl Beta-D-Glucosaminidase (NAGase)
kl014Ra02 骨成型蛋白4(BMP4)多克隆抗體 Polyclonal Antibody to Bone Morphogenetic Protein 4 (BMP4)
kl013Po02 骨成型蛋白2(BMP2)多克隆抗體 Polyclonal Antibody to Bone Morphogenetic Protein 2 (BMP2)
kl013Ca02 骨成型蛋白2(BMP2)多克隆抗體 Polyclonal Antibody to Bone Morphogenetic Protein 2 (BMP2)
kl008Mu02 血管生成素1(ANGPT1)多克隆抗體 Polyclonal Antibody to Angiopoietin 1 (ANGPT1)
kl008Hu02 血管生成素1(ANGPT1)多克隆抗體 Polyclonal Antibody to Angiopoietin 1 (ANGPT1)
kl336Hu02 信號(hào)素4B(SEMA4B)多克隆抗體 Polyclonal Antibody to Semaphorin 4B (SEMA4B)
kl892Hu04 角蛋白81(KRT81)多克隆抗體 Polyclonal Antibody to Keratin 81 (KRT81)
