產(chǎn)品詳情
簡單介紹：
Anti-phospho-BCAR1 (Tyr751)抗體產(chǎn)品質(zhì)量穩(wěn)定，實驗效果明顯，貨期快，價格優(yōu)惠，歡迎垂詢訂購！我公司長期供應(yīng)**組化抗體、WB抗體、**組化試劑盒和抗體試驗所需全部相關(guān)試劑、熒光標記抗體、單克隆抗體、多克隆抗體、各種標記的二抗IgG/IgM/IgD/IgA等科研實驗抗體。Anti-phospho-BCAR1 (Tyr751)抗體用于**組化實驗,WB實驗,相應(yīng)的標記抗體有HRP標記抗體,FITC標記,BIO等。
詳情介紹：
Rabbit Anti-phospho-BCAR1 (Tyr751)
Cat. Number:
Anti-phospho-BCAR1 (Tyr751)抗體KL-12575R
Quantity size:
0.1ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
p130 represents one of several known substrates for v-Crk encoded p47. p130 Cas (for Crk-associated substrate) Anti-phospho-BCAR1 (Tyr751)抗體exhibits a high level of tyrosine phosphorylation and is tightly associated with v-Crk, suggesting a role in v-Crk-mediated cell signaling. The molecular cloning of p130 Cas has shown it to represent a novel SH3 containing signaling molecule with a cluster of multiple putative SH2-binding motifs for v-Crk. By immunoprecipitation analysis, p130 Cas has been shown to be highly phosphorylated at tyrosine residues subsequent to either v-Src p60 or v-Crk-mediated transformation and to form stable complexes with both of these transforming proteins. p130 Cas behaves as an extremely potent substrate for protein tyrosine kinases and has been reported to relocate from the cytoplasm to cell membrane upon tyrosine phosphorylation. One proposed model is that the SH2 domain of v-Crk functions to activate c-Src Anti-phospho-BCAR1 (Tyr751)抗體kinase, which in turn phosphorylates p130 Cas.
Also known as:
BCAR1 (phospho Y751); BCAR1(phospho Y751); p-BCAR1(p-Tyr751); Breast cancer anti estrogen resistance 1 protein; BCAR Anti-phospho-BCAR1 (Tyr751)抗體1; Bcar1; BCAR1_HUMAN; Breast cancer anti estrogen resistance 1; Breast cancer anti-estrogen resistance protein 1; CAS; Cas scaffolding protein family member 1; Crk associated substrate; Crk associated substrate p130Cas; CRK-associated substrate; CRKAS; P130CAS.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, Mouse, Rat, .
●
Immunogen: KLH conjugated synthesised phosphopeptide derived from human BCAR1 around the phosphorylation site of Tyr751.
●
Predicted Molecular Weight: 93kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500Anti-phospho-BCAR1 (Tyr751)抗體 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
kl125Hu01 著絲粒蛋白B(CENPB)多克隆抗體 Polyclonal Antibody to Centromere Protein B (CENPB)
kl127Bo01 脫氧核糖核酸酶Ⅰ(DNASE1)多克隆抗體 Polyclonal Antibody to Deoxyribonuclease I (DNASE1)
kl127Hu01 脫氧核糖核酸酶Ⅰ(DNASE1)多克隆抗體 Polyclonal Antibody to Deoxyribonuclease I (DNASE1)
kl127Mu01 脫氧核糖核酸酶Ⅰ(DNASE1)多克隆抗體 Polyclonal Antibody to Deoxyribonuclease I (DNASE1)
kl134Hu01 黑色素瘤關(guān)聯(lián)硫酸軟骨素蛋白聚糖(MCSP)多克隆抗體 Polyclonal Antibody to Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP)
kl137Hu01 造骨細胞鈣黏蛋白(CDHOB)多克隆抗體 Polyclonal Antibody to Cadherin, Osteoblast (CDHOB)
kl143Hu01 CD24分子(CD24)多克隆抗體 Polyclonal Antibody to Cluster Of Differentiation 24 (CD24)
kl144Hu01 唾液酸結(jié)合Ig樣凝集素2(SIGLEC2)多克隆抗體 Polyclonal Antibody to Sialic Acid Binding Ig Like Lectin 2 (SIGLEC2)
kl151Hu01 磷脂酶A1(PLA1)多克隆抗體 Polyclonal Antibody to Phospholikle A1 (PLA1)
kl154Hu01 纖維蛋白原α(FGα)多克隆抗體 Polyclonal Antibody to Fibrinogen Alpha (FGa)
kl154Mu01 纖維蛋白原α(FGα)多克隆抗體 Polyclonal Antibody to Fibrinogen Alpha (FGa)
kl154Ra01 纖維蛋白原α(FGα)多克隆抗體 Polyclonal Antibody to Fibrinogen Alpha (FGa)
kl160Hu01 抗增生抗體靶分子1(TAPA1)多克隆抗體 Polyclonal Antibody to Target Of The Antiproliferative Antibody 1 (TAPA1)
kl162Hu01 硫氧還蛋白結(jié)合蛋白2(TBP2)多克隆抗體 Polyclonal Antibody to Thioredoxin Binding Protein 2 (TBP2)
kl162Mu01 硫氧還蛋白結(jié)合蛋白2(TBP2)多克隆抗體 Polyclonal Antibody to Thioredoxin Binding Protein 2 (TBP2)
kl163Hu01 磷脂爬行酶2(PLSCR2)多克隆抗體 Polyclonal Antibody to Phospholipid Scramblase 2 (PLSCR2)
kl164Hu01 發(fā)動蛋白2(DNM2)多克隆抗體 Polyclonal Antibody to Dynamin 2 (DNM2)
kl166Hu01 VGF神經(jīng)生長因子誘導(dǎo)蛋白(VGF)多克隆抗體 Polyclonal Antibody to VGF Nerve Growth Factor Inducible (VGF)
kl166Mu01 VGF神經(jīng)生長因子誘導(dǎo)蛋白(VGF)多克隆抗體 Polyclonal Antibody to VGF Nerve Growth Factor Inducible (VGF)
